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Ritlecitinib tosylate CAS NO.2192215-81-7
- Min.Order: 100 Gram
- Payment Terms: L/C,T/T
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- Product Details
Keywords
- Ritlecitinib tosylate
- PF-06651600
- Ritlecitinib
Quick Details
- ProName: Ritlecitinib tosylate
- CasNo: 2192215-81-7
- Molecular Formula: C22H27N5O4S
- Appearance: white powder
- Application: A potent and selective JAK3 inhibitor
- DeliveryTime: 2 months
- PackAge: fiber can
- Port: shanghai port
- ProductionCapacity: 100 Kilogram/Year
- Purity: 99%
- Storage: store at 2-8 ℃
- Transportation: air transport
- LimitNum: 100 Gram
- Related Substances: ≤0.1%
- Residue on Ignition: ≤0.1%
- Heavy Metal: ≤20ppm
- Valid Period: 2 years
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Details
Name Ritlecitinib tosylate
The chemical name is 1-{(2S,5R)-2-methyl-5-[(7H-pyrrolo[2,3-d]pyrimidin-4-yl)amino]piperidin-1-yl}prop-2-en-1-one tosylate
Synonym Ritlecitinib tosylate; Ritlecitinib; PF-06651600; PF 06651600; PF06651600; PF-6651600; PF 6651600; PF6651600;
English synonyms Ritlecitinib tosylate; Ritlecitinib; PF-06651600; PF 06651600; PF06651600; PF-6651600; PF 6651600; PF6651600;
Molecular formula C22H27N5O4S
Molecular weight 457.55
Cas number 2192215-81-7
itlecitinib, also known as PF-06651600, is a potent and selective JAK3 inhibitor. PF-06651600 is a potent and low clearance compound with demonstrated in vivo efficacy. The favorable efficacy and safety profile of this JAK3-specific inhibitor PF-06651600 led to its evaluation in several human clinical studies. JAK3 was among the first of the JAKs targeted for therapeutic intervention due to the strong validation provided by human SCID patients displaying JAK3 deficiencies.