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Home > Products >  ALK-IN-27

ALK-IN-27 CAS NO.2739866-40-9

  • Min.Order: 100 Gram
  • Payment Terms: L/C,T/T
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  • Product Details

Keywords

  • ALK-IN-27
  • NVL-655
  • (R)-1-chloro-3-ethyl-12-fluoro-10,16-dimethyl-3,10,16,18-tetrahydro-4,8-(metheno)benzo[l]dipyrazolo[3,4-g:4',3'-j][1]oxa[4]azacyclotetradecin-7-amine

Quick Details

  • ProName: ALK-IN-27
  • CasNo: 2739866-40-9
  • Molecular Formula: C23H22ClFN6O
  • Appearance: white powder
  • Application: NVL-655 (ALK-in-27) is a novel, brain ...
  • DeliveryTime: 2 months
  • PackAge: fiber can
  • Port: shanghai port
  • ProductionCapacity: 100 Kilogram/Year
  • Purity: 99%
  • Storage: store at 2-8℃
  • Transportation: air transport
  • LimitNum: 100 Gram
  • Related Substances: <0.1%
  • Residue on Ignition: <0.1%
  • Heavy Metal: <20ppm
  • Valid Period: 2 years

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Details

English name: ALK-IN-27 English synonym ALK-IN-27; (R) - 1 - chloro - 3 - baton rouge - 12 - fluoro - 10 - dimethyl - 23,10,16,18 - tetrahydro - 4, 8 - (metheno) benzo [l] dipyrazolo [3, 4 - g: 4, '3' - j] [1] oxa [4]azacyclotetradecin-7-amine; Chemicalbook (R) - 1 - chloro - 3 - baton rouge - 12 - fluoro - 10 - dimethyl - 23,10,16,18 - tetrahydro - 4, 8 - (metheno) benzo [l] dipyrazolo [3, 4 - g: 4 ' ,3'-j][1]oxa[4]azacyclotetradecin-7-amine

CAS number 2739866-40-9

Molecular formula C23H22ClFN6O

Molecular weight 452.91

The Predicted density was 1.46±0.1g/cm3(Temp:20°C; Press: 7 )

(Predicted) acidity coefficient (pKa) 7.11 + / - 0.40

(Predicted) forms a solid color white to rice white

Storage Dry, dark and at 0 - 4℃ for short term (days to weeks) or -20℃ for long term (months to years).
Solubility Soluble in DMSO
Handling Refer to MSDS
Shipping Condition Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.
HS Code 2934200090

NVL-655 is a novel brain-osmotic ALK selective inhibitor designed to address unmet needs that exist in currently available ALK inhibitors, including therapeutic resistance, brain metastases, and off-target central nervous system (CNS) adverse effects associated with TRK inhibition (AE).

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