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GS-441524 CAS NO.1191237-69-0
- Min.Order: 1 Kilogram
- Payment Terms: L/C,T/T
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- Product Details
Keywords
- GS-441524
- GS 441524(acid)
- 2-C-(4-AMINOPYRROLO[2,1-F][1,2,4]TRIAZIN-7-YL)-2,5-ANHYDRO-3,4-O-(1-METHYLETHYLIDENE)-D-ALTRONONITRI
Quick Details
- ProName: GS-441524
- CasNo: 1191237-69-0
- Molecular Formula: C12H13N5O4
- Appearance: white powder
- Application: GS-441524 (GS441524), the main active ...
- DeliveryTime: 2 months
- PackAge: fiber can
- Port: shanghai port
- ProductionCapacity: 100 Kilogram/Year
- Purity: 99%
- Storage: store at 2-8 ℃
- Transportation: air transport
- LimitNum: 1 Kilogram
- Related Substances: ≤0.1%
- Residue on Ignition: ≤0.1%
- Heavy Metal: ≤20ppm
- Valid Period: 2 years
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Details
English name GS-441524
English synonyms (2R,3R,4S,5R)-2-(4-aminopyrrolo [2, 1-f][1,2,4]TRIAZIN-7-YL)-3, 4-dihydroxy-5 -(HYDROXYMETHYL)OXOLANE-2-; (2 r, 3 r, 4 s, 5 r) - 2 - (4 - Aminopyrrolo 4-trichlorobenzene [1] [2, 1 - f] triazin - 7 - yl) - 3, 4 - dihydroxy - 5 - (hydroxymethyl) oxolane - 2 - carbonitrile; 2 - C - (4 - AMINOPYRROLO 4-trichlorobenzene [1] [2, 1 - F] TRIAZIN - 7 - YL) - 2, 5 - ANHYDRO - 3, 4 - O - (1 - METHYLETHYLIDENE) - D - ALTRONONITRI; (2 r, 3 r, 4 s, 5 r) - 2 - (4 - aminopyrrolo [2, 1 - f] [1, 4-trichlorobenzene Chemicalbook] triazin - 7 - yl) - 3, 4 - dihydroxy - 5 - (hydroxymethyl) tetrahydrofuran - 2 - carbonitrile; D - Altrononitrile, 2 - C - (4 - aminopyrrolo 4-trichlorobenzene [1] [2, 1 - f] triazin - 7 - yl) - 2, 5 - anhydro -; 2 - C - (4 - Aminopyrrolo 4-trichlorobenzene [1] [2, 1 - f] triazin - 7 - yl) - 2, 5 - anhydro - D - Altrononitrile; GS441525; (2R,3R,4S,5R)-2-(4-aminopyrrolo [2, 1-f][1,2,4]TRIAZIN-7-YL)-3, 4-Dihydroxy-5 -(HYDROXYMETHYL)TETRAHYDRO
CAS No. 1191237-69-0
Molecular formula C 12H13N5O4
Melting point >233°C(dec.)
Density 1.84±0.1g/cm3(Predicted) Storage conditions -20°C
Solubility in DMSO(>25mg/mChemicalbookl)
Acidity coefficient (pKa)12.13±0.70(Predicted)
Form solid color off-white stability can be stored in DMSO solution at -20°C for up to 1 month
molecular weight 291.26
GS-441524 is a small molecule, riboside triphosphate competitive inhibitor, that has demonstrated strong antiviral activity against many RNA viruses. It can inhibit the replication of several different types of RNA viruses, such as zoonotic severe acute respiratory syndrome (SARS) coronavirus, Middle East Respiratory syndrome virus, Ebola virus, Lassa fever virus, Junin virus, and respiratory syncytial virus, while having low cytotoxicity in a wide range of cell lines.