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Home > Products >  Entrectinib

Entrectinib CAS NO.1108743-60-7

  • Min.Order: 1 Kilogram
  • Payment Terms: L/C,T/T
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  • Product Details

Keywords

  • Entrectinib
  • Entrectinib(NMS-E628)
  • N-(5-(3,5-difluorobenzyl)-1H-indazol-3-yl)-4-(4-methylpiperazin-1-yl)-2-(tetrahydro-2H-pyran-4-ylamino)benzamide

Quick Details

  • ProName: Entrectinib
  • CasNo: 1108743-60-7
  • Molecular Formula: C31H34F2N6O2
  • Appearance: white powder
  • Application: Entrectinib is a potent, orally active...
  • DeliveryTime: 2 months
  • PackAge: fiber can
  • Port: shanghai port
  • ProductionCapacity: 200 Kilogram/Year
  • Purity: 99%
  • Storage: Store at 2-8°C
  • Transportation: air transport
  • LimitNum: 1 Kilogram
  • Related Substances: ≤0.1%
  • Residue on Ignition: ≤0.1%
  • Heavy Metal: ≤20ppm
  • Valid Period: 2 years

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Details

English name: Entrectinib

English synonyms: N-[5-[(3, 5-difluorophenyl)methyl] -1h-indazol-3-yl]-4-(4-methyl-1-piperazinyl)-2-[(tetrChemicalbookahydro-2H-pyran-4) -yl)amino]benzamide; Entrectinib; Entrectinib(NMS-E628); N - (5 - (3, 5 - difluorobenzyl) 1 h - indazol - 3 - yl) - 4 - (4 - methylpiperazin - 1 - yl) - 2 - (tetrahydro - 2 h - pyran 4 - ylamino) benzamide; RXDX-101; Entrectinib,NMS-E628,RXDX-101; entrecitinib; Entrectinib(RXDX-101)

CAS number: 1108743-60-7

Molecular formula :C31H34F2N6O2

Molecular weight :560.64

Entrectinib is a potent, orally active inhibitor of Trk, ROS1, and ALK; The IC50 values for inhibiting TrkA, TrkB, TrkC, ROS1 and ALK were 1, 3, 5, 12 and 7 nM, respectively.

 

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