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Larotrectinib Sulfate CAS NO.1223405-08-0
- Min.Order: 1 Kilogram
- Payment Terms: L/C,T/T
- Available Specifications:
- Product Details
Keywords
- LOXO-101 (sulfate)
- (3S)-N-[5-[(2R)-2-(2,5-Difluorophenyl)-1-pyrrolidinyl]pyrazolo[1,5-a]pyrimidin-3-yl]-3-hydroxy-1-pyrrolidinecarboxamide sulfate (1:1)
- Larotrectinib Sulfate
Quick Details
- ProName: Larotrectinib Sulfate
- CasNo: 1223405-08-0
- Molecular Formula: C21H24F2N6O6S
- Appearance: light yellow powder
- Application: Larotinib is a broad-spectrum anticanc...
- DeliveryTime: 2 months
- PackAge: fiber can
- Port: shanghai port
- ProductionCapacity: 100 Kilogram/Year
- Purity: 99%
- Storage: room temperature
- Transportation: air transport
- LimitNum: 1 Kilogram
- Related Substances: ≤0.1%
- Residue on Ignition: ≤0.1%
- Heavy Metal: ≤20ppm
- Valid Period: 2 years
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Details
CAS number :1223405-08-0
English name :LarotrectinibSulfate
English alias :LOX-101; Loxo-101 (S); LOX-101(sulfate); ARRY470)sulfate; LOXO-101(sulfate); Larotrectinibsulfate; Larotrectinib(LOXO101; ARRY-470,Larotrectinib; LarotrectinibsulfatesaltChemicalbook; Larotrectinibsulfate (LOXO101)
Molecular formula :C21H24F2N6O6S
Molecular weight :526.52
MOLFile:1223405-08-0.mol
Storage condition :Storeat-20°C
Solubility :≥18.47mg/mLinDMSO; Acuity 2.14 mg/mLinEtOH;
Form :solid
Color :Lightyellowtobrown
Stability :Hygroscopic
Larotrectinib sulfate (LOXO-101, ARY-470) is an orally available, selective, and effective inhibitor of ATP-competitive tropomyosin receptor kinase TRK. Larotrectinib inhibits TRKs and induces apoptosis and G1 cell cycle arrest.